Ms. Meane — E.S. Mooney

The Powerpuff Girls is Cartoon Network's highest-rated show among kids 2-11 -- and the #1 licence in the U.S. for all of 2001! Scholastic's Valentine Book hit #9 on the NY Times Kids' Bestsellers.Something very strange is happening at Pokey Oaks Kindergarten. The Powerpuff Girls' super-sweet teacher Ms. Keane has suddenly become... Ms. Meane! Now it's up to The Powerpuff Girls to save their classmates from her evil clutches. But first they'll have to figure out which of Townsville's villains is behind this pernicious plot.