
Charles, poor boy from up state New York, whose goal is wealth and social status. He sets up practice in the City of New York; however, when legitimate means don't produce financial rewards quickly enough, he resorts to criminal activity, consorting with members of the underworld and making himself vulnerable to blackmail.
Abner, a farm boy from rural Illinois, inspired by the doctor who cared for his family. His altruistic motives turn to disappointment when reality replaces dreams. Returning to his hometown, he is met with resentment and hostility and must decide to leave or stay and fight.
David, the rich boy from San Francisco. The only son of a wealthy businessman, he chooses medical school to escape his parents and their plans for him to carry on the family business. An adventurer and ladies man, tragedy strikes just as he finds purpose in his life.